Article
Support vector machine algorithms in the search of KIR gene associations with disease.
Computers in biology and medicine - 1 Dec 2013
Cuevas Tello Juan C, Hernández-Ramírez Daniel, García-Sepúlveda Christian A
Abstract excerpt
Killer-cell immunoglobulin-like receptors (KIR) are membrane proteins expressed by natural killer cells and CD8 lymphocytes. The KIR system consists of 17 genes and 614 alleles, some of which bind human leukocyte antigens (HLA). Both KIR and HLA modulate susceptibility to haematological malignancies, viral infections and autoimmune diseases. Molecular epidemiology studies employ traditional statistical methods to...
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