Article
The clinicopathological significance and relationship of Gli1, MDM2 and p53 expression in resectable pancreatic cancer.
Histopathology - 1 Mar 2014
Sheng Weiwei, Dong Ming, Zhou Jianping, Li Xin, Liu Qingfeng, Dong Qi, Li Feng
Abstract excerpt
AIMS: To study the expression of Gli1, MDM2 and p53 for clinical significance in pancreatic cancer (PC), and their functional relationship in regulating the biological behaviour of PC cells. METHODS AND RESULTS: Immunohistochemistry showed that the expression of Gli1, MDM2 and p53 was much higher in 57 cases of PC than in paired normal pancreatic tissues, and was positively associated with tumour UICC stage and T...
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