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Human Cytomegalovirus Manipulation of Latently Infected Cells

21 Nov 2013

Abstract excerpt

Primary infection with human cytomegalovirus (HCMV) results in the establishment of a lifelong infection of the host which is aided by the ability of HCMV to undergo a latent infection. One site of HCMV latency in vivo is in haematopoietic progenitor cells, resident in the bone marrow, with genome carriage and reactivation being restricted to the cells of the myeloid lineage. Until recently, HCMV latency has been...

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PMID: 24284875
DOI: 10.3390/v5112803

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