Article
Ultra-deep sequencing of intra-host rabies virus populations during cross-species transmission.
PLoS neglected tropical diseases - 1 Nov 2013
Borucki Monica K, Chen-Harris Haiyin, Lao Victoria, Vanier Gilda, Wadford Debra A, Messenger Sharon, Allen Jonathan E
Abstract excerpt
One of the hurdles to understanding the role of viral quasispecies in RNA virus cross-species transmission (CST) events is the need to analyze a densely sampled outbreak using deep sequencing in order to measure the amount of mutation occurring on a small time scale. In 2009, the California Department of Public Health reported a dramatic increase (350) in the number of gray foxes infected with a rabies virus...
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