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Article

First molecular analysis of F8 gene in algeria: identification of two novel mutations.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Oct 2014

Abdi Meriem, Zemani-Fodil Faouzia, Fodil Mostefa, Aberkane Meriem Samia, Touhami Hadj, Saidi-Mehtar Nadhira, Costa Catherine, Boudjema Abdallah

Abstract excerpt

The aim of this study was to detect the genetic alterations in the Factor 8 gene in 26 patients from Western Algeria. We detected the presence of "intron 22 inversion" with long-range polymerase chain reaction (PCR). Negative patients for this inversion were analyzed for "intron 1 inversion" using multiplex PCR. Patients who were negative for both inversions were analyzed using a direct sequencing. Deleterious...

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PMID: 24270469
DOI: 10.1177/1076029613513321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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