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Article

Crosstalk between VEGF and MTA1 signaling pathways contribute to aggressiveness of breast carcinoma

22 Nov 2013

Abstract excerpt

The expression of metastasis associated protein (MTA1) correlates well with tumor metastasis; however its role as a proangiogenic protein and the molecular mechanisms underlying the same are not fully understood. In this study the MTA1 protein was expressed and purified to evaluate its angiogenic potential. In both MCF-7 and MDA-MB-231 cells, endogenous MTA1 protein was localized in the nucleus; while added...

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PMID: 24265228
DOI: 10.1002/mc.22104

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