Article
Transcriptome signatures of class I and III stress response deregulation in Lactobacillus plantarum reveal pleiotropic adaptation.
Microbial cell factories - 18 Nov 2013
Van Bokhorst-van de Veen Hermien, Bongers Roger S, Wels Michiel, Bron Peter A, Kleerebezem Michiel
Abstract excerpt
BACKGROUND: To cope with environmental challenges bacteria possess sophisticated defense mechanisms that involve stress-induced adaptive responses. The canonical stress regulators CtsR and HrcA play a central role in the adaptations to a plethora of stresses in a variety of organisms. Here, we determined the CtsR and HrcA regulons of the lactic acid bacterium Lactobacillus plantarum WCFS1 grown under reference...
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