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Lack of association between the polymorphisms of hypoxia-inducible factor 1A (HIF1A) gene and SLE susceptibility in a Chinese population.

Immunogenetics - 1 Jan 2014

Feng Chen-Chen, Ye Qian-Ling, Zhu Yan, Leng Rui-Xue, Chen Gui-Mei, Yang Jie, Cen Han, Yang Xiao-Ke, Li Rui, Xu Wang-Dong, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

Hypoxia-inducible factor 1 (HIF-1) introduced the immune imbalance between Th17 and Treg cells, which may play an important role in the pathogenesis of systemic lupus erythematosus (SLE). The aim of the present study was to determine whether the HIF1A gene influences the susceptibility to SLE. A study on this relationship has not been conducted to date. A total of 3,793 subjects (1,497 SLE patients and 2,296...

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PMID: 24232601
DOI: 10.1007/s00251-013-0743-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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