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Article

Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2014

Kang Justin J, Shu Liming, Park James L, Shayman James A, Bodary Peter F

Abstract excerpt

A defect in the gene for the lysosomal enzyme α-galactosidase A (Gla) results in globotriaosylceramide (Gb3) accumulation in Fabry disease and leads to premature death from cardiac and cerebrovascular events. However, gastrointestinal symptoms are often first observed during childhood in these pa...

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Identifiers

PMID: 24232002
DOI: 10.1152/ajpgi.00185.2013
PMCID: PMC3920075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24232002-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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