Article
A hierarchical frailty model for familial testicular germ-cell tumors.
American journal of epidemiology - 15 Feb 2014
Valberg Morten, Grotmol Tom, Tretli Steinar, Veierød Marit B, Moger Tron A, Aalen Odd O
Abstract excerpt
Using a 2-level hierarchical frailty model, we analyzed population-wide data on testicular germ-cell tumor (TGCT) status in 1,135,320 two-generational Norwegian families to examine the risk of TGCT in family members of patients. Follow-up extended from 1954 (cases) or 1960 (unaffected persons) to 2008. The first-level frailty variable was compound Poisson-distributed. The underlying Poisson parameter was...
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