Article
Transfer of specificity by murine alpha and beta T-cell receptor genes.
Nature - 1 Jan 2000
Dembić Z, Haas W, Weiss S, McCubrey J, Kiefer H, von Boehmer H, Steinmetz M
Abstract excerpt
T-cell receptor alpha- and beta-chain genes were isolated from a class I major histocompatibility complex-restricted cytotoxic T-cell clone and transferred by protoplast fusion into another cytolytic T-cell clone of different specificity. Expression of the transfected alpha and beta genes endowed the recipient cell with the specificity of the donor cell.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.