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Article

Integrative gene set analysis: application to platinum pharmacogenomics.

Omics : a journal of integrative biology - 1 Jan 2014

Fridley Brooke L, Abo Ryan, Tan Xiang-Lin, Jenkins Gregory D, Batzler Anthony, Moyer Ann M, Biernacka Joanna M, Wang Liewei

Abstract excerpt

Integrative genomics has the potential to uncover relevant loci, as clinical outcome and response to chemotherapies are most likely not due to a single gene (or data type) but rather a complex relationship involving genetic variation, mRNA, DNA methylation, and copy number variation. In addition to this complexity, many complex phenotypes are thought to be controlled by the interplay of multiple genes within the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24199607
DOI: 10.1089/omi.2013.0099
PMCID: PMC3903166

Genes

CENPF
LMNB1

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