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Article

Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.

British journal of cancer - 10 Dec 2013

Aparicio T, Svrcek M, Zaanan A, Beohou E, Laforest A, Afchain P, Mitry Emmanuel, Taieb J, Di Fiore F, Gornet J-M, Thirot-Bidault A, Sobhani I, Malka D, Lecomte T, Locher C, Bonnetain F, Laurent-Puig P

Abstract excerpt

BACKGROUND: Small bowel adenocarcinoma (SBA) is a rare tumour with a poor prognosis. Molecular biology data on SBA carcinogenesis are lacking. METHODS: Expression of HER2, β-catenin, p53 and mismatch repair (MMR) protein was assessed by immunohistochemistry. KRAS, V600E BRAF mutations and microsatellite instability were investigated. RESULTS: We obtained samples from 63 SBA patients (tumour stages: I-II: 30%;...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24196786
DOI: 10.1038/bjc.2013.677
PMCID: PMC3859950

Genes

KRAS
BRAF

Variants

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Source receipt: pubmed, retrieved 7 Sept 2026.

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