Article
Role of quantitative and qualitative characteristics of free circulating DNA in the management of patients with non-small cell lung cancer.
Cellular oncology (Dordrecht, Netherlands) - 1 Dec 2013
Ulivi Paola, Silvestrini Rosella
Abstract excerpt
BACKGROUND: The release of DNA into peripheral blood is a common event in cancer patients, occurring as a consequence of necrotic and apoptotic processes typical of tumor cells. However, free circulating DNA (fcDNA) is also present in patients with benign diseases and in healthy individuals. Both quantitative and qualitative aspects of fcDNA have been studied as potential biomarkers in a number of tumor types. In...
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