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Article

Can we predict which patients are likely to develop severe complications following reconstruction for osteoradionecrosis?

The British journal of oral & maxillofacial surgery - 1 Dec 2013

Lyons Andrew J, Nixon Iain, Papadopoulou Dionyssia, Crichton Siobhan

Abstract excerpt

High morbidity has been reported for free vascularised reconstruction for osteoradionecrosis (ORN) and there are no apparent risk factors. A single nucleotide polymorphism in the transforming growth factor beta 1 gene (TGF-β1) has been implicated in the cause of ORN and may also predict these complications. We studied a series of 30 consecutive patients who had had reconstruction for severe ORN with free tissue...

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PMID: 24176184
DOI: 10.1016/j.bjoms.2013.08.017

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