Cytokinesis-required Cdc14 is a signaling hub of asexual development and multi-stress tolerance in Beauveria bassiana.

doi:10.1038/srep03086

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Article

Cytokinesis-required Cdc14 is a signaling hub of asexual development and multi-stress tolerance in Beauveria bassiana.

Scientific reports - 30 Oct 2013

Wang Jie, Liu Jing, Hu Yue, Ying Sheng-Hua, Feng Ming-Guang

Abstract excerpt

A dual-specificity, paralogue-free Cdc14 phosphatase was located in the nuclei of Beauveria bassiana (filamentous entomopathogen) and functionally characterized. Inactivation of cdc14 caused defective cytokinesis due to multinucleate cells formed in Δcdc14 and 89% decrease of blastospore production, followed by slower growth and a loss of ≥ 96% conidial yield under normal conditions. These defects coincided well...

Topics

Adaptation, Biological
Beauveria
Cytokinesis
Fungal Proteins
Gene Deletion
Gene Expression Regulation, Fungal
Gene-Environment Interaction
Phenotype
Phosphorylation
Protein Tyrosine Phosphatases
Signal Transduction
Stress, Physiological
Transcriptome

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Identifiers

PMID: 24169500
DOI: 10.1038/srep03086
PMCID: PMC3812655

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