Article
Characterization of two distinct neuraminidases from avian-origin human-infecting H7N9 influenza viruses.
Cell research - 1 Dec 2013
Wu Yan, Bi Yuhai, Vavricka Christopher J, Sun Xiaoman, Zhang Yanfang, Gao Feng, Zhao Min, Xiao Haixia, Qin Chengfeng, He Jianhua, Liu Wenjun, Yan Jinghua, Qi Jianxun, Gao George F
Abstract excerpt
An epidemic of an avian-origin H7N9 influenza virus has recently emerged in China, infecting 134 patients of which 45 have died. This is the first time that an influenza virus harboring an N9 serotype neuraminidase (NA) has been known to infect humans. H7N9 viruses are divergent and at least two distinct NAs and hemagglutinins (HAs) have been found, respectively, from clinical isolates. The prototypes of these...
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