Article
miR-181 and metabolic regulation in the immune system.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2013
Williams Adam, Henao-Mejia Jorge, Harman Christian C D, Flavell Richard A
Abstract excerpt
Regulation of metabolism is emerging as a central mechanism to control cellular identity and function. Extensive research in the last few years has revealed that the PI3K pathway is at the forefront of establishing metabolic changes required for immune cell growth, proliferation, migration, and differentiation. However, we currently have a limited understanding of how signaling through the PI3K pathway is tightly...
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