Article
Diagnosis, surveillance, and treatment strategies for familial adenomatous polyposis: rationale and update.
European journal of gastroenterology & hepatology - 1 Mar 2014
Aihara Hiroyuki, Kumar Nitin, Thompson Christopher C
Abstract excerpt
Familial adenomatous polyposis is characterized by the development of multiple (>100) colorectal adenomas throughout the colorectum. This disorder can be caused by a germline mutation in the adenomatous polyposis coli gene and can be diagnosed either clinically or genetically. After diagnosis with the condition, patients should undergo prophylactic proctocolectomy with a neoreservoir, usually an ileoanal pouch,...
Topics
- Adenomatous Polyposis Coli
- Anticarcinogenic Agents
- Capsule Endoscopy
- Genes, APC
- Genetic Testing
- Germ-Line Mutation
- Humans
- Mutation
- Population Surveillance
- Proctocolectomy, Restorative