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Article

Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat.

Disease models & mechanisms - 1 Jan 2014

Suárez Juan, Rivera Patricia, Arrabal Sergio, Crespillo Ana, Serrano Antonia, Baixeras Elena, Pavón Francisco J, Cifuentes Manuel, Nogueiras Rubén, Ballesteros Joan, Dieguez Carlos, Rodríguez de Fonseca Fernando

Abstract excerpt

β-adrenergic receptor activation promotes brown adipose tissue (BAT) β-oxidation and thermogenesis by burning fatty acids during uncoupling respiration. Oleoylethanolamide (OEA) can inhibit feeding and stimulate lipolysis by activating peroxisome proliferator-activating receptor-α (PPARα) in white adipose tissue (WAT). Here we explore whether PPARα activation potentiates the effect of β3-adrenergic stimulation on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24159189
DOI: 10.1242/dmm.013110
PMCID: PMC3882055

Genes

TNF
UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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