Article
Basic fibroblast growth factor/vascular endothelial growth factor in the serum from severe burn patients stimulates the proliferation of cultured human umbilical cord mesenchymal stem cells via activation of Notch signaling pathways.
The journal of trauma and acute care surgery - 1 Nov 2013
Liu Ling-Ying, Hou Yu-Sen, Chai Jia-Ke, Hu Quan, Duan Hong-Jie, Yu Yong-Hui, Yin Hui-Nan, Hao Dai-Feng, Feng Guang, Li Tao, Du Jun-Dong
Abstract excerpt
BACKGROUND: Mesenchymal stem cells (MSCs) are the leading cellular constituents used in regenerative medicine. MSCs repair and reconstruct wounds of acute traumata and radiation-induced burns through proliferation, differentiation, and trophic activity. However, repair effect of MSCs on severe burn wounds remain to be clarified because severe burns are much more complex traumata than radiation-induced burns....
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