Article
A systematic review of definitions of extreme phenotypes of HIV control and progression.
AIDS (London, England) - 14 Jan 2014
Gurdasani Deepti, Iles Louise, Dillon David G, Young Elizabeth H, Olson Ashley D, Naranbhai Vivek, Fidler Sarah, Gkrania-Klotsas Effrossyni, Post Frank A, Kellam Paul, Porter Kholoud, Sandhu Manjinder S
Abstract excerpt
The study of individuals at opposite ends of the HIV clinical spectrum can provide invaluable insights into HIV biology. Heterogeneity in criteria used to define these individuals can introduce inconsistencies in results from research and make it difficult to identify biological mechanisms underlying these phenotypes. In this systematic review, we formally quantified the heterogeneity in definitions used for...
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