Article
Comparative analysis of error-prone replication mononucleotide repeats across baculovirus genomes.
Virus research - 26 Dec 2013
Ream David C, Murakami Samuel T, Schmidt Emily E, Huang Guo-Hua, Liang Chun, Friedberg Iddo, Cheng Xiao-Wen
Abstract excerpt
Genome replication by the baculovirus DNA polymerase often generates errors in mononucleotide repeat (MNR) sequences due to replication slippage. This results in the inactivation of genes that affects different stages of the cell infection cycle. Here we mapped these MNRs in the 59 baculovirus genomes. We found that the MNR frequencies of baculovirus genomes are different and not correlated with the genome sizes....
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