Article
Acceptability of chemoprevention trials in high-risk subjects.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2013
Bonanni B, Lazzeroni M
Abstract excerpt
The development and current widespread acceptance of clinical trials is one of the major conceptual advances in research medicine introduced during the second half of the 20th century. Despite general agreement on the scientific merits of randomization, many patients and physicians are however reluctant to participate in randomized, controlled trials. If we focus on chemoprevention in healthy subjects, it is even...
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