Article
Decreased bone mineral density in subjects carrying familial defective apolipoprotein B-100.
The Journal of clinical endocrinology and metabolism - 1 Dec 2013
Yerges-Armstrong Laura M, Shen Haiqing, Ryan Kathleen A, Streeten Elizabeth A, Shuldiner Alan R, Mitchell Braxton D
Abstract excerpt
CONTEXT: Although numerous epidemiologic studies have documented associations between osteoporosis and cardiovascular disease, the mechanisms underlying this association remain to be clarified. One hypothesis is that hyperlipidemia may be a common predisposing factor to both atherosclerotic heart disease and bone fragility. OBJECTIVE: To evaluate this, we compared bone mineral density (BMD) between subjects with...
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