Article
Accumulating mutations in series of haplotypes at the KIT and MITF loci are major determinants of white markings in Franches-Montagnes horses.
PloS one - 1 Jan 2013
Haase Bianca, Signer-Hasler Heidi, Binns Matthew M, Obexer-Ruff Gabriela, Hauswirth Regula, Bellone Rebecca R, Burger Dominik, Rieder Stefan, Wade Claire M, Leeb Tosso
Abstract excerpt
Coat color and pattern variations in domestic animals are frequently inherited as simple monogenic traits, but a number are known to have a complex genetic basis. While the analysis of complex trait data remains a challenge in all species, we can use the reduced haplotypic diversity in domestic animal populations to gain insight into the genomic interactions underlying complex phenotypes. White face and leg...
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