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Article

Cordycepin Regulates GSK-3β/β-Catenin Signaling in Human Leukemia Cells

26 Sept 2013

Abstract excerpt

BACKGROUND: Leukemia stem cells (LSCs) are a limitless cell source for the initiation and maintenance of leukemia. Activation of the Wnt/β-catenin pathway is required for the survival and development of LSCs. Therefore, targeting β-catenin is considered a therapeutic strategy for the treatment of leukemia. The goal of this study was to explore whether cordycepin, an active component of the traditional medicine...

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PMID: 24086728
DOI: 10.1371/journal.pone.0076320

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