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Article

Deep sequencing identifies two genotypes and high viral genetic diversity of human pegivirus (GB virus C) in rural Ugandan patients.

The Journal of general virology - 1 Dec 2013

Ghai Ria R, Sibley Samuel D, Lauck Michael, Dinis Jorge M, Bailey Adam L, Chapman Colin A, Omeja Patrick, Friedrich Thomas C, O'Connor David H, Goldberg Tony L

Abstract excerpt

Human pegivirus (HPgV), formerly 'GB virus C' or 'hepatitis G virus', is a member of the genus Flavivirus (Flaviviridae) that has garnered significant attention due to its inhibition of HIV, including slowing disease progression and prolonging survival in HIV-infected patients. Currently, there are six proposed HPgV genotypes that have roughly distinct geographical distributions. Genotypes 2 and 3 are the most...

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Flaviviridae Infections
GB virus C
Genome, Viral
Hepatitis, Viral, Human
High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rural Population

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Identifiers

PMID: 24077364
DOI: 10.1099/vir.0.055509-0
PMCID: PMC3836497

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