Article
The next-generation sequencing revolution and its impact on genomics.
Cell - 26 Sept 2013
Koboldt Daniel C, Steinberg Karyn Meltz, Larson David E, Wilson Richard K, Mardis Elaine R
Abstract excerpt
Genomics is a relatively new scientific discipline, having DNA sequencing as its core technology. As technology has improved the cost and scale of genome characterization over sequencing's 40-year history, the scope of inquiry has commensurately broadened. Massively parallel sequencing has proven revolutionary, shifting the paradigm of genomics to address biological questions at a genome-wide scale. Sequencing...
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