Article
Impact of the next-generation sequencing data depth on various biological result inferences.
Science China. Life sciences - 1 Feb 2013
Hou Rui, Yang Zhenxing, Li Minghui, Xiao Huasheng
Abstract excerpt
Next-generation sequencing (NGS) technologies have revolutionized the field of genomics and provided unprecedented opportunities for high-throughput analysis at the levels of genomics, transcriptomics and epigenetics. However, the cost of NGS is still prohibitive for many laboratories. It is imperative to address the trade-off between the sequencing depth and cost. In this review, we will discuss the effects of...
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