Article
Non-invasive sampling of schistosomes from humans requires correcting for family structure.
PLoS neglected tropical diseases - 1 Jan 2013
Steinauer Michelle L, Christie Mark R, Blouin Michael S, Agola Lelo E, Mwangi Ibrahim N, Maina Geoffrey M, Mutuku Martin W, Kinuthia Joseph M, Mkoji Gerald M, Loker Eric S
Abstract excerpt
For ethical and logistical reasons, population-genetic studies of parasites often rely on the non-invasive sampling of offspring shed from their definitive hosts. However, if the sampled offspring are naturally derived from a small number of parents, then the strong family structure can result in biased population-level estimates of genetic parameters, particularly if reproductive output is skewed. Here, we...
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