Article
Prevalence and familial aggregation of schistosomal liver morbidity in Kenya: evaluation by new ultrasound criteria.
The Journal of infectious diseases - 15 Mar 2001
Kariuki H C, Mbugua G, Magak P, Bailey J A, Muchiri E M, Thiongo F W, King C H, Butterworth A E, Ouma J H, Blanton R E
Abstract excerpt
Severe periportal fibrosis is not an inevitable consequence of infection with Schistosoma mansoni. Genetic predisposition may be a deciding factor in the development of disease. To assess the contribution of genetic factors in the severity of hepatic fibrosis, the degree of familial aggregation was determined in a Kenyan population. Schistosomal fibrosis was identified with hepatic ultrasound and newly proposed...
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