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Article

The L Gene of J Paramyxovirus Plays a Critical Role in Viral Pathogenesis

26 Sept 2013

Abstract excerpt

J paramyxovirus (JPV) was first isolated from moribund mice with hemorrhagic lung lesions in Australia in the 1970s. Recent sequencing of JPV (JPV-LW) confirms that JPV is a paramyxovirus with several unique features. However, neither JPV-LW nor a recombinant JPV based on its sequence (rJPV-LW) caused obvious illness in mice. In this work, we analyzed a different JPV isolate (JPV-BH), which behaved differently...

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PMID: 24067956
DOI: 10.1128/jvi.02039-13

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