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Article

BCov: a method for predicting β-sheet topology using sparse inverse covariance estimation and integer programming.

Bioinformatics (Oxford, England) - 15 Dec 2013

Savojardo Castrense, Fariselli Piero, Martelli Pier Luigi, Casadio Rita

Abstract excerpt

MOTIVATION: Prediction of protein residue contacts, even at the coarse-grain level, can help in finding solutions to the protein structure prediction problem. Unlike α-helices that are locally stabilized, β-sheets result from pairwise hydrogen bonding of two or more disjoint regions of the protein backbone. The problem of predicting contacts among β-strands in proteins has been addressed by several supervised...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24064422
DOI: 10.1093/bioinformatics/btt555
PMCID: PMC5994943

Genes

MCC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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