Article
Failure of moxifloxacin treatment in Mycoplasma genitalium infections due to macrolide and fluoroquinolone resistance.
International journal of STD & AIDS - 1 Oct 2013
Couldwell Deborah L, Tagg Kaitlin A, Jeoffreys Neisha J, Gilbert Gwendolyn L
Abstract excerpt
Increasing azithromycin treatment failure in sexually transmitted Mycoplasma genitalium infection, is linked to macrolide resistance and second-line treatment relies on the fluoroquinolone, moxifloxacin. We recently detected fluoroquinolone and macrolide resistance-associated mutations in 15% and 43%, respectively, of 143 initial M. genitalium PCR-positive specimens. For a subset of 33 Western Sydney Sexual...
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