Article
Phase 2 trial of rituximab and bortezomib in patients with relapsed or refractory mantle cell and follicular lymphoma.
Cancer - 1 Jun 2011
Baiocchi Robert A, Alinari Lapo, Lustberg Mark E, Lin Thomas S, Porcu Pierluigi, Li Xiaobai, Johnston Jeffrey S, Byrd John C, Blum Kristie A
Abstract excerpt
BACKGROUND: In vitro studies in mantle cell lymphoma (MCL) cell lines and patient-derived cells have demonstrated synergistic apoptosis with combined rituximab and bortezomib (R-bortezomib) compared with single-agent bortezomib. Therefore, the authors of this report evaluated R-bortezomib in a pr...
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