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A Host-Based RT-PCR Gene Expression Signature to Identify Acute Respiratory Viral Infection

18 Sept 2013

Abstract excerpt

Improved ways to diagnose acute respiratory viral infections could decrease inappropriate antibacterial use and serve as a vital triage mechanism in the event of a potential viral pandemic. Measurement of the host response to infection is an alternative to pathogen-based diagnostic testing and may improve diagnostic accuracy. We have developed a host-based assay with a reverse transcription polymerase chain...

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PMID: 24048524
DOI: 10.1126/scitranslmed.3006280

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