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Global Patterns of Diversity and Selection in Human Tyrosinase Gene

11 Sept 2013

Abstract excerpt

Global variation in skin pigmentation is one of the most striking examples of environmental adaptation in humans. More than two hundred loci have been identified as candidate genes in model organisms and a few tens of these have been found to be significantly associated with human skin pigmentation in genome-wide association studies. However, the evolutionary history of different pigmentation genes is rather...

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PMID: 24040225
DOI: 10.1371/journal.pone.0074307

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