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Article

Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans

1 Jan 2008

Abstract excerpt

BACKGROUND: The observed correlation between ultraviolet light incidence and skin color, together with the geographical apportionment of skin reflectance among human populations, suggests an adaptive value for the pigmentation of the human skin. We have used Affymetrix U133a v2.0 gene expression microarrays to investigate the expression profiles of a total of 9 melanocyte cell lines (5 from lightly pigmented...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 18312627
DOI: 10.1186/1471-2148-8-74

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