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Article

SOX9 duplication linked to intersex in deer.

PloS one - 1 Jan 2013

Kropatsch Regina, Dekomien Gabriele, Akkad Denis A, Gerding Wanda M, Petrasch-Parwez Elisabeth, Young Neil D, Altmüller Janine, Nürnberg Peter, Gasser Robin B, Epplen Jörg T

Abstract excerpt

A complex network of genes determines sex in mammals. Here, we studied a European roe deer with an intersex phenotype that was consistent with a XY genotype with incomplete male-determination. Whole genome sequencing and quantitative real-time PCR analyses revealed a triple dose of the SOX9 gene, allowing insights into a new genetic defect in a wild animal.

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Share to Disorders of Sex Development
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24040047
DOI: 10.1371/journal.pone.0073734
PMCID: PMC3765313

Genes

SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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