Article
EGFR exon-level biomarkers of the response to bevacizumab/erlotinib in non-small cell lung cancer.
PloS one - 1 Jan 2013
Baty Florent, Rothschild Sacha, Früh Martin, Betticher Daniel, Dröge Cornelia, Cathomas Richard, Rauch Daniel, Gautschi Oliver, Bubendorf Lukas, Crowe Susanne, Zappa Francesco, Pless Miklos, Brutsche Martin
Abstract excerpt
Activating epidermal growth factor receptor (EGFR) mutations are recognized biomarkers for patients with metastatic non-small cell lung cancer (NSCLC) treated with EGFR tyrosine kinase inhibitors (TKIs). EGFR TKIs can also have activity against NSCLC without EGFR mutations, requiring the identifi...
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