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Article

Epimorphin-induced MET sensitizes ovarian cancer cells to platinum.

PloS one - 1 Jan 2013

Yew Kok-Hooi, Crow Jennifer, Hirst Jeff, Pessetto Ziyan, Pressetto Ziyan, Godwin Andrew K

Abstract excerpt

Distinctive genotypic and phenotypic features of ovarian cancer via epithelial-mesenchymal transition (EMT) have been correlated with drug resistance and disease recurrence. We investigated whether therapeutic reversal of EMT could re-sensitize ovarian cancer cells (OCCs) to existing chemotherapy...

Read the complete abstract on PubMed

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Source

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Identifiers

PMID: 24039787
DOI: 10.1371/journal.pone.0072637
PMCID: PMC3767807

Genes

MET
KLF4
MMP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24039787-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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