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Article

Clinically significant missense variants in human GALNT3, GALNT8, GALNT12, and GALNT13 genes: intriguing in silico findings.

Journal of cellular biochemistry - 1 Feb 2014

Hussain Muhammad Ramzan Manwar, Nasir Jamal, Al-Aama Jumana Yousuf

Abstract excerpt

Aberrant glycosylation by N-acetylgalactosaminyl transferases (GALNTs) is a well-described pathological alteration that is widespread in hereditary diseases, prominently including human cancers, familial tumoral calcinosis and hyperostosis-hyperphosphatemia. In this study, we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Mutation, Missense

Share to N-Acetylgalactosaminyltransferases

Share to Polymorphism, Single Nucleotide

Share to Polypeptide N-acetylgalactosaminyltransferase

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 24038392
DOI: 10.1002/jcb.24666

Genes

GALNT12
GALNT3
GALNT13
GALNT8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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