Article
Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations.
Hepatology (Baltimore, Md.) - 1 Feb 2014
Kleiner David E, Chalasani Naga P, Lee William M, Fontana Robert J, Bonkovsky Herbert L, Watkins Paul B, Hayashi Paul H, Davern Timothy J, Navarro Victor, Reddy Rajender, Talwalkar Jayant A, Stolz Andrew, Gu Jiezhun, Barnhart Huiman, Hoofnagle Jay H
Abstract excerpt
UNLABELLED: Drug-induced liver injury (DILI) is considered to be a diagnosis of exclusion. Liver biopsy may contribute to diagnostic accuracy, but the histological features of DILI and their relationship to biochemical parameters and outcomes are not well defined. We have classified the pathological pattern of liver injury and systematically evaluated histological changes in liver biopsies obtained from 249...
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