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Article

A directed approach for the identification of transcripts harbouring the spliced leader sequence and the effect of trans-splicing knockdown in Schistosoma mansoni.

Memorias do Instituto Oswaldo Cruz - 1 Sept 2013

Mourão Marina de Moraes, Bitar Mainá, Lobo Francisco Pereira, Peconick Ana Paula, Grynberg Priscila, Prosdocimi Francisco, Waisberg Michael, Cerqueira Gustavo Coutinho, Macedo Andréa Mara, Machado Carlos Renato, Yoshino Timothy, Franco Glória Regina

Abstract excerpt

Schistosomiasis is a major neglected tropical disease caused by trematodes from the genus Schistosoma. Because schistosomes exhibit a complex life cycle and numerous mechanisms for regulating gene expression, it is believed that spliced leader (SL) trans-splicing could play an important role in the biology of these parasites. The purpose of this study was to investigate the function of trans-splicing in...

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Identifiers

PMID: 24037192
DOI: 10.1590/0074-0276108062013006
PMCID: PMC3970683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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