Article
Association of endothelin-converting enzyme-1b C-338A polymorphism with increased risk of ischemic stroke in Chinese Han population.
Journal of molecular neuroscience : MN - 1 Oct 2013
Li Rui, Cui Min, Zhao Jin, Yu Mingming, Ying Zegang, Zhou Shiming, Zhou Huadong
Abstract excerpt
Endothelin-converting enzyme-1b (ECE-1b) C-338A is a polymorphism located in ECE-1 gene promoter, which has been reported to correlate with the risk of carotid atherosclerosis. We conducted a hospital-based case-control study of 309 patients with ischemic stroke and 309 controls matched on age and gender. The frequencies of ECE-1b-338 CC, CA, and AA genotypes in cases (45.0, 40.4, and 14.6 %) were significantly...
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