Article
Loss of all three calreticulins, CRT1, CRT2 and CRT3, causes enhanced sensitivity to water stress in Arabidopsis.
Plant cell reports - 1 Dec 2013
Kim Jun Hyeok, Nguyen Nguyen Hoai, Nguyen Ngoc Trinh, Hong Suk-Whan, Lee Hojoung
Abstract excerpt
KEY MESSAGE: The calreticulin triple knockout mutant shows growth defects in response to abiotic stress. The endoplasmic reticulum (ER) is an essential organelle that is responsible for the folding and maturation of proteins. During ER stress, unfolded protein aggregates accumulate in the cell, leading to the unfolded protein response (UPR). The UPR up-regulates the expression of ER-stress-responsive genes...
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