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Article

Effect of copy number variants on outcomes for infants with single ventricle heart defects.

Circulation. Cardiovascular genetics - 1 Oct 2013

Carey Abigail S, Liang Li, Edwards Jonathan, Brandt Tracy, Mei Hui, Sharp Andrew J, Hsu Daphne T, Newburger Jane W, Ohye Richard G, Chung Wendy K, Russell Mark W, Rosenfeld Jill A, Shaffer Lisa G, Parides Michael K, Edelmann Lisa, Gelb Bruce D

Abstract excerpt

BACKGROUND: Human genomes harbor copy number variants (CNVs), which are regions of DNA gains or losses. Although pathogenic CNVs are associated with congenital heart disease (CHD), their effect on clinical outcomes is unknown. This study sought to determine whether pathogenic CNVs among infants with single ventricle physiology were associated with inferior neurocognitive and somatic growth outcomes. METHODS AND...

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Share to Comparative Genomic Hybridization
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gap Junction alpha-5 Protein

Share to GATA4 Transcription Factor

Share to Genome, Human

Share to Heart Defects, Congenital

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Source

Open in PubMed Open full text

Identifiers

PMID: 24021551
DOI: 10.1161/CIRCGENETICS.113.000189
PMCID: PMC3987966

Genes

GATA4
GJA5
MYH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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