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Article

Perturbations of mechanotransduction and aneurysm formation in heritable aortopathies.

International journal of cardiology - 25 Oct 2013

Jeremy Richmond W, Robertson Elizabeth, Lu Yaxin, Hambly Brett D

Abstract excerpt

Thoracic aortic aneurysm and dissection in young and middle aged patients is increasingly recognised as due to genetic aortopathy. Mutations in multiple genes affecting proteins in the extracellular matrix, microfibrillar structure, the endothelium and cell signalling pathways have been associate...

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Share to Aortic Aneurysm, Thoracic
Share to Aortic Dissection
Share to Mechanotransduction, Cellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24016541
DOI: 10.1016/j.ijcard.2013.08.056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24016541-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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