Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras.

PloS one - 1 Jan 2013

Garcia Mayra L, Reynolds Tracy D, Mothes Walther, Robek Michael D

Abstract excerpt

The hepatitis B virus (HBV) Core protein encodes a late (L)-domain like motif (129PPAYRPPNAP(138)) that has been purported to serve as a docking site for recruitment of host factors such as Nedd4 that can mediate viral particle release from infected cells. However, mutation of this region of Core typically disrupts nucleocapsid formation in the cytoplasm, making it difficult to ascertain if the Core PPAY motif...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endosomal Sorting Complexes Required for Transport
Share to Gene Order

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Products, gag

Share to Leukemia Virus, Murine

Share to Nedd4 Ubiquitin Protein Ligases

Share to Protein Interaction Domains and Motifs

Share to Viral Core Proteins

Share to Virus Release

Source

Open in PubMed Open full text

Identifiers

PMID: 24009707
DOI: 10.1371/journal.pone.0072845
PMCID: PMC3756966

Genes

WWP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras.PMID 24009707Read ↗

Viral Late DomainsSemantic proximity Read ↗

Regulation of Hepatitis B Virus Virion Release and Envelopment Timing by Nucleocapsid and Envelope Interactions.Semantic proximity Read ↗

Functional Replacement of a Retroviral Late Domain by Ubiquitin FusionSemantic proximity Read ↗

Late Domain Function Identified in the Vesicular Stomatitis Virus M Protein by Use of Rhabdovirus-Retrovirus ChimerasSemantic proximity Read ↗

Multiple roles of core protein linker in hepatitis B virus replicationSemantic proximity Read ↗

The Adenovirus L4 33-Kilodalton Protein Binds to Intragenic Sequences of the Major Late Promoter Required for Late Phase-Specific Stimulation of TranscriptionSemantic proximity Read ↗

Late assembly motifs of human T-cell leukemia virus type 1 and their relative roles in particle release.Semantic proximity Read ↗

Hepatitis B virus replication and release are independent of core lysine ubiquitination.Semantic proximity Read ↗

Analysis of bovine leukemia virus gag membrane targeting and late domain function.Semantic proximity Read ↗

Rescue of HIV-1 Release by Targeting Widely Divergent NEDD4-Type Ubiquitin Ligases and Isolated Catalytic HECT Domains to GagSemantic proximity Read ↗

Functional involvement of a novel Nedd4-like ubiquitin ligase on retrovirus budding.Semantic proximity Read ↗

Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.